Danshen Extract

Danshen, the dried root of Salvia miltiorrhiza Bunge, has been a cornerstone of traditional herbal wisdom for centuries, revered for its support of circulatory and cardiovascular health. Modern pharmacological research has validated its traditional uses and uncovered a broader spectrum of bioactivity. As a premier B2B supplier, we provide standardized, high-potency Danshen Extract, meticulously processed to preserve its unique dual-profile of active compounds: the lipophilic Tanshinones and the hydrophilic Salvianolic Acids. This extract is engineered for formulators seeking a scientifically-backed, multi-target botanical ingredient for advanced nutraceutical applications.

Authenticity and traceability are paramount. Our Danshen is sourced from certified cultivation bases in regions of China renowned for premium Salvia miltiorrhiza, such as Shandong and Shaanxi provinces. We work with partners who employ Good Agricultural and Collection Practices (GACP), ensuring sustainable harvesting of roots typically at 3-4 years of age for optimal phytochemical content. Each batch of raw material undergoes rigorous macroscopic and microscopic identification, as well as HPLC fingerprinting, to confirm it is genuine Salvia miltiorrhiza Bunge, differentiating it from other Salvia species.

The efficacy of Danshen stems from its complex interplay of two distinct chemical families. Our extract is standardized to guarantee consistent levels of key markers from both groups.

* Primary Active Constituents:

Lipophilic Diterpene Quinones (Tanshinones):

Tanshinone IIA: The most significant and studied marker compound in this group, known for its cardiovascular and antioxidant activities.

Cryptotanshinone, Tanshinone I.

* Hydrophilic Phenolic Acids (Salvianolic Acids):

Salvianolic Acid B: The most abundant and potent water-soluble antioxidant in Danshen, with significant neuroprotective and anti-fibrotic properties.

Rosmarinic Acid, Salvianolic Acid A.

Standardization Options: We offer extracts standardized to Total Tanshinones (e.g., 2%, 5%, 10%), Tanshinone IIA (e.g., 1%, 5%), or Salvianolic Acid B (e.g., 20%, 50%). The 10:1 ratio full-spectrum extract is also available.

Quality is quantified. Our comprehensive COA provides full transparency and ensures adherence to stringent specifications.

Typical COA Specifications Table (For Tanshinone IIA 5% Standardized Extract):

Our cGMP-compliant process is designed to efficiently co-extract and preserve both the lipophilic and hydrophilic active fractions.

Raw Material Preparation: Certified roots are cleaned, sliced, and dried under controlled conditions to preserve actives.

* Multi-Stage Extraction: We employ dynamic multi-stage extraction technology, often using food-grade ethanol-water mixtures at optimized temperatures and durations to achieve a high yield of both Tanshinones and Salvianolic Acids.

* Separation & Purification: The crude extract undergoes low-temperature concentration, followed by advanced membrane filtration and chromatographic techniques (where applicable for high-standardization products) to remove impurities, enrich target compounds, and reduce solvent residues.

* Standardization & Blending: The purified extract is analytically tested and blended to meet the exact standardization specifications (e.g., Tanshinone IIA 5%).

* Drying & Packaging: The final product is dried using vacuum drying or spray drying and packaged in a controlled environment to ensure stability.

* Dual-Action Standardization: Guaranteed levels of both Tanshinone IIA and Salvianolic Acid B, capturing the holistic, synergistic activity of Danshen.

* High Bioavailability Formats: We offer advanced formulations, including water-dispersible powder forms of Tanshinones, overcoming solubility challenges for enhanced bioavailability.

* Full Spectrum of Actives: Our process is optimized to preserve a broad profile of beneficial compounds, not just isolated markers.

* Stringent Safety Profile: Produced in a GMP-certified facility with rigorous control over heavy metals, microbes, and solvent residues. Non-GMO, Allergen-Free.

* Stability & Consistency: Excellent shelf stability with batch-to-batch consistency verified by HPLC fingerprinting.

A robust body of scientific research, including numerous clinical trials, supports Danshen's applications:

* Cardiovascular & Microcirculatory Support: Promotes healthy blood flow. Tanshinone IIA has been studied for its role in supporting endothelial function and healthy platelet activity (Source: Acta Pharmacologica Sinica). Salvianolic Acid B is a potent protector against vascular endothelial oxidative stress.

* Antioxidant & Anti-inflammatory Activity: Salvianolic Acid B is one of nature's most potent phenolic antioxidants, effectively scavenging free radicals and modulating inflammatory pathways like NF-κB.

* Neuroprotective & Cognitive Support: Exhibits protective effects on neurons, supports healthy cerebral blood flow, and may aid memory and cognitive function, making it relevant for brain health formulations (Source: Oxidative Medicine and Cellular Longevity).

* Liver Health Support: Shows hepatoprotective properties by modulating antioxidant defenses and inflammatory responses in the liver.

Our standardized Danshen Extract is ideal for sophisticated formulations in:

* Cardiovascular Health Supplements: Capsules, tablets, and softgels targeting circulatory support, healthy blood pressure already within normal range, and overall heart health.

* Cognitive & Brain Health Formulas: Combined with other nootropics and neuroprotective agents in products for memory, focus, and long-term cognitive support.

* Antioxidant & General Wellness Blends: As a potent, natural antioxidant component in comprehensive wellness products.

* Women's Health Formulas: Particularly in products addressing wellness during menopause, leveraging its traditional use and circulatory support.

* Liver Support Complexes: Incorporated into detox and hepatoprotective supplement blends.

* Standard Packaging: 1 kg / 5 kg in sealed, food-grade polyethylene bags within aluminum foil bags. Packed in clean, durable cardboard cartons.

* Bulk Packaging: 25 kg fiber drum with double polyethylene liner for high-volume manufacturing.

* Storage: Store in a cool (<20°C), dry, and dark place. Keep container tightly sealed to protect from moisture and oxidation.

* Shelf Life: 24 months from the production date when stored under recommended conditions.

* Global Shipping: We provide reliable global logistics via air or sea freight, with comprehensive documentation including COA, MSDS, Certificate of Analysis, and Certificate of Origin. Samples available for qualified B2B clients.

JOYWIN attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

As customer focus has never been so important for today's enterprises, we believe that only a customer-focused company will win renewed loyalty and competitive advantage.
At JOYWIN, Our team of professionals is committed to providing superior and personalized service to meet all your needs.

Q1: What is the difference between a 10:1 extract and a Tanshinone IIA 5% extract?
A: A 10:1 extract is a full-spectrum concentrate where 10 kg of raw herb yields 1 kg of powder, with variable active content. A Tanshinone IIA 5% extract is precisely standardized to contain a guaranteed minimum of 5% of this key marker compound, ensuring consistent, dose-dependent efficacy and is preferred for clinical-grade formulations.

Q2: Is Danshen safe to use in dietary supplements? Are there any known interactions?
A: Danshen has a long history of safe use. However, due to its effects on circulation and platelet activity, it is often recommended to avoid concurrent use with anticoagulant/antiplatelet pharmaceutical drugs (e.g., warfarin, aspirin). We recommend our clients include appropriate disclaimer language on their finished product labels. Always advise consultation with a healthcare professional.

Q3: Can you provide a water-soluble form of Tanshinones?
A: Yes. Through advanced carrier and encapsulation technologies, we offer water-dispersible Danshen extracts where the lipophilic Tanshinones are effectively delivered into aqueous systems, significantly improving bioavailability and application versatility.

Q4: What certifications do you hold for this product?
A: Our manufacturing is conducted in a cGMP, ISO 22000 certified facility. The product is Kosher and Halal certified upon request. We also provide Third-Party Lab Test Reports for verification.

Q5: Do you offer custom standardization ratios or blends?
A: Absolutely. We specialize in custom extraction and standardization. We can tailor the ratio of Tanshinones to Salvianolic Acids, create specific blends with other complementary extracts (e.g., Ginkgo, Hawthorn), or develop proprietary formulas to your exact specifications.

Q6: What is the typical lead time for orders?
A: For standardized stock products, lead time is 10-15 working days after order confirmation. For custom projects, the timeline will be determined based on the project scope and quantity.

Q7：Where & how can I place an order?
A：You can click the inquiry on Danshen extract or send us an e-mail to contact@joywinworld.com.

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