Glycyrrhizin Powder

Glycyrrhizin Powder

Source: Glabridin Licorice
Part of use: Root
Appearance: white powder
Sample: Free
Application: medicine, cosmetics, supplement
Delivery time: 7-8 working days for air freight
Transportation method: DHL, FEDEX, TNT and so on, by sea and by air...

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Product Introduction

Products Description

Glycyrrhizin Powder, the primary bioactive triterpenoid saponin derived from Glycyrrhiza glabra (licorice root), represents one of nature's most versatile and potent functional ingredients. Renowned for its intense sweetness-50-200 times sweeter than sucrose-and its remarkable anti-inflammatory and soothing properties, our high-purity Glycyrrhizin is engineered for discerning manufacturers in the nutraceutical, functional food, and pharmaceutical industries.

We specialize in supplying a standardized, high-potency extract that delivers consistent, reliable performance. This ingredient allows you to develop innovative products that cater to the growing demand for natural sweeteners, respiratory health support, and gentle wellness solutions.

 

Product Source & Traceability

Botanical Integrity from Seed to Extract

The quality of our Glycyrrhizin is rooted in the quality of our raw material. We source our licorice root from cultivated, sustainably managed farms in Xinjiang, China, and Mediterranean regions, areas celebrated for producing licorice with high glycyrrhizinic acid content.

* Botanical Name: Glycyrrhiza glabra L.

* Plant Part Used: Carefully selected roots and stolons, typically 3-4 years old for optimal potency.

* Cultivation Standard: Sourced from partners adhering to Good Agricultural and Collection Practices (GACP).

* Identity & Purity: Every batch of raw material is verified through macroscopic and microscopic inspection and TLC/HPLC testing to ensure botanical authenticity and the absence of contaminating species.

 

Key Active Composition

Our Glycyrrhizin Powder is meticulously standardized to guarantee a high and consistent concentration of the key active constituent, providing predictable efficacy in your formulations.

Active Compound

Specification

Chemical Profile & Significance

Glycyrrhizinic Acid

≥ 95% (HPLC)

The primary triterpenoid saponin responsible for the characteristic sweetness, anti-inflammatory, and antiviral activities.

Related Saponins & Flavonoids

Balanced Profile

Includes trace amounts of other bioactive compounds like glabridin and liquiritin, which may contribute to the holistic activity profile.

Glycyrrhizin powder

 

Product Specifications & Certificate of Analysis (COA)

Every batch of our Glycyrrhizin is supported by a comprehensive Certificate of Analysis from an ISO 17025 accredited laboratory, ensuring it meets the highest standards of purity and safety.

Typical Specification Sheet:

Parameter

Specification

Test Method

Appearance

Fine, white to off-white powder

Visual

Odor & Taste

Characteristic, intensely sweet

Organoleptic

Assay (HPLC)

Glycyrrhizinic Acid ≥ 95%

HPLC

Mesh Size

100% pass 80 mesh

Sieve Analysis

Loss on Drying

≤ 5.0%

Karl Fischer / Thermo-gravimetric

Sulfated Ash

≤ 1.0%

Gravimetric

Heavy Metals

   

Lead (Pb)

< 3 mg/kg

ICP-MS

Arsenic (As)

< 2 mg/kg

ICP-MS

Cadmium (Cd)

< 1 mg/kg

ICP-MS

Mercury (Hg)

< 0.1 mg/kg

ICP-MS

Microbiological Analysis

   

Total Plate Count

< 1,000 CFU/g

USP <61>

Yeast & Mold

< 100 CFU/g

USP <61>

E. Coli**

Negative

USP <62>

Salmonella**

Negative

USP <62>

Residual Solvents

Meets ICH Q3C Guidelines

GC

 

Manufacturing Process & Quality Control

Advanced Extraction & Purification for Pharmaceutical-Grade Quality

Our manufacturing process is designed to concentrate Glycyrrhizinic Acid while rigorously removing impurities, adhering to cGMP (Current Good Manufacturing Practices) guidelines.

* Raw Material Preparation: Licorice roots are washed, dried, and comminuted to a uniform size.

* Solvent Extraction: The root material undergoes a targeted extraction process using water and/or ethanol to isolate the bioactive compounds.

* Concentration & Precipitation: The extract is concentrated under vacuum, and glycyrrhizin is precipitated to achieve a crude form.

* Purification & Crystallization: Advanced purification techniques, including re-crystallization, are employed to remove pigments, resins, and other impurities, yielding a high-purity, crystalline powder.

* Drying & Milling: The purified crystals are dried under controlled conditions and milled to a consistent, free-flowing powder.

* Quality Control & Release: The final product undergoes rigorous in-process and final testing against a comprehensive set of specifications before release.

 

Product Features & Key Advantages

* Exceptional Purity: Guaranteed ≥ 95% Glycyrrhizinic Acid content, ensuring potent and consistent biological activity.

* High-Intensity Natural Sweetener: Offers a sweetness profile 50-200 times that of sucrose, with a slower onset and longer-lasting effect, ideal for sugar-reduction applications.

* Superior Solubility: Our powder exhibits excellent solubility in water, facilitating easy incorporation into liquid formulations, syrups, and beverages.

* Dual-Functionality: Functions as both a potent bioactive ingredient and a natural flavor modulator/sweetener.

* cGMP & ISO-Certified Production: Manufactured in facilities that comply with international quality and safety standards.

 

Scientifically Supported Health Benefits

The efficacy of Glycyrrhizin is supported by a substantial body of pharmacological research.

* Soothes Respiratory Discomfort & Supports Immunity: Glycyrrhizin is renowned for its demulcent and expectorant properties, helping to soothe irritated mucous membranes in the throat and airways. It also exhibits immunomodulatory and broad-spectrum antiviral activity. 

* Powerful Anti-inflammatory & Antioxidant Action: It mimics the action of cortisol by inhibiting 11-beta-hydroxysteroid dehydrogenase, contributing to its significant anti-inflammatory effects. It also scavenges free radicals, reducing oxidative stress. 

* Supports Gastrointestinal Health: Glycyrrhizin and its metabolites have been shown to possess gastro-protective properties, potentially inhibiting the growth of H. pylori and soothing gastric discomfort.

* Adrenocortical Function: It has a documented history of use in supporting adrenal gland function and helping the body adapt to stress.

* Important Safety Note: Due to its mineralocorticoid-like activity, high-dose or prolonged consumption of Glycyrrhizin can lead to increased blood pressure and hypokalemia. We provide full technical guidance on safe usage levels for your specific applications.

 

Product Applications

Our high-purity Glycyrrhizin Powder is incredibly versatile for a range of product development needs:

* Dietary Supplements: Throat lozenges, respiratory health formulas, immune support blends, and adrenal support capsules.

* Functional Foods & Beverages: Used as a natural sweetener and functional ingredient in herbal teas, health tonics, sugar-free confectionery, and functional chewing gums.

* Pharmaceuticals: An active ingredient in cough syrups, sore throat preparations, and gastro-protective formulations.

* Flavor Modulator: Used to mask bitter tastes and enhance the overall flavor profile of nutraceutical products.

 

Packaging & Logistics

We guarantee the integrity of your product from our facility to your production line.

* Standard Packaging: 1 kg per aluminum foil bag, vacuum-sealed. 25 kg per fiber drum.

* Custom Packaging: Available upon request to meet your specific needs.

* Storage: Store in a cool, dry, and well-ventilated place. Keep away from direct light and moisture.

* Shelf Life: 24 months when stored in unopened packaging under recommended conditions.

* Global Shipping: We offer reliable global logistics with flexible terms (FOB, CIF, DAP) to suit your supply chain requirements.

 

JOYWIN Manufacturing Facilities

JOYWIN founded in 2013 is an innovation-driven biotechnology company. we provide the manufacture of plant extracts, plant proteases, and customized products. We believe Good produce= Integrity+ Technology+Quality Control.

product-1040-500

 

JOYWIN Technical Support

● R&D team of 40 members to provide full technical support.
● Years of successful experience with top food companies in the world.
● Dedicate on build long-term relationships with our clients and developing deeps partnership.

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Frequently Asked Questions

Q1: What is the recommended usage level for Glycyrrhizin?
A: Usage levels vary significantly based on the application-as a sweetener or as a bioactive. For sweetening, levels are typically very low (0.1-0.3%). For therapeutic applications, it is crucial to adhere to regional regulatory limits (e.g., EFSA recommends a maximum of 100 mg/day of glycyrrhizinic acid). Our technical team can provide specific guidance.

Q2: Can you supply Ammoniated Glycyrrhizin?
A: Yes. We can produce Glycyrrhizin in both its acid form and as Ammoniated Glycyrrhizin, which offers improved water solubility for certain applications like beverages.

Q3: Is your product compliant with global regulatory standards?
A: Our product is manufactured to meet major pharmacopoeial standards (USP, EP). We provide full documentation to support your regulatory submissions in North America, Europe, and other key markets.

Q4: How does Glycyrrhizin compare to artificial sweeteners?
A: As a naturally derived sweetener, it aligns with clean-label trends. It provides sweetness with a licorice-like aftertaste and offers additional functional health benefits, unlike most synthetic sweeteners.

Q5: What technical support do you offer?
A: We provide comprehensive support, including formulation advice, dosage recommendations, regulatory documentation (COA, MSDS, GMO/Allergen Statements), and custom extraction services.

Q6:How can we contact you?
A:You can click the inquiry on Glycyrrhizin powder or send us an e-mail to contact@joywinworld.com.

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