Quercetin Dihydrate Powder

JoyWin Natural presents our premium Quercetin Dihydrate Powder, a highly purified, plant-derived flavonoid compound standardized to a minimum of 98% purity. Quercetin is one of the most extensively researched bioflavonoids, renowned for its potent antioxidant and cellular signaling modulation properties. The dihydrate form (with two water molecules of crystallization, C₁₅H₁₀O₇·2H₂O) offers superior stability and handling characteristics compared to the anhydrous variant, making it the preferred choice for high-quality supplement manufacturing.

Engineered for B2B applications, our Quercetin Dihydrate serves as a fundamental active ingredient for formulating advanced dietary supplements targeting immune support, antioxidant defense, cardiovascular health, and overall metabolic wellness. We provide the consistent, high-purity foundation your brand needs to develop scientifically backed, efficacious products in a competitive market.

Our Quercetin is not synthetic but is derived from natural botanical precursors through a sophisticated process.

* Primary Natural Precursor: It is primarily obtained via the hydrolysis of Rutin (Quercetin-3-rutinoside), a flavonoid glycoside abundantly found in plants like Sophora japonica (Pagoda Tree) buds and Fava D'Anta.

* Sourcing Integrity: We source high-grade Rutin from trusted, audited suppliers whose cultivation and harvesting practices meet our stringent quality and sustainability criteria.

* Manufacturing Expertise: The conversion from Rutin to high-purity Quercetin Dihydrate is conducted in our state-of-the-art, GMP-compliant partner facilities. This process involves controlled hydrolysis, followed by multiple crystallization and purification steps to achieve pharmaceutical-grade purity.

Quercetin Dihydrate is a specific crystalline form of the quercetin molecule with defined chemical properties.

Every batch of JoyWin Natural Quercetin Dihydrate is subjected to rigorous identity, purity, and safety testing via HPLC, UV, and other advanced analytical methods.

A Representative COA Includes:

A full, batch-specific COA is provided with all shipments, ensuring full transparency and compliance for your quality systems.

Our manufacturing process is designed to maximize purity and ensure the consistent formation of the stable dihydrate crystal.

1.Raw Material (Rutin) Qualification: Incoming Rutin is tested for identity and purity.

2.Acid Hydrolysis: Rutin undergoes controlled acid hydrolysis in a food-grade solvent system to cleave the rutinose sugar moiety, releasing the quercetin aglycone.

3.Crystallization & Isolation: The crude quercetin is crystallized under precise temperature and pH conditions to initiate the formation of the dihydrate crystal structure.

4.Multiple Purification Steps: The crystals undergo successive recrystallization steps from appropriate solvents to remove any residual impurities, color bodies, or by-products.

5.Drying & Milling: The purified Quercetin Dihydrate crystals are gently dried under controlled humidity to preserve the water of crystallization, then milled to a uniform, free-flowing powder of specified mesh size.

6.Blending & Homogenization: Powder from multiple crystallization batches is blended to ensure exceptional lot-to-lot consistency in purity and performance.

7.Final QC & Release: The finished batch must pass our exhaustive final testing against all COA specifications before approval for packaging.

* Exceptional Purity: Guaranteed ≥98% Quercetin content (on dried basis), minimizing filler and ensuring potent, reliable dosing in your final products.

* Stable Dihydrate Form: The crystalline dihydrate offers superior long-term stability, reduced dusting, and better flowability compared to anhydrous forms, simplifying manufacturing.

* Natural-Derived, Not Synthetic: Sourced from natural Rutin, appealing to consumers seeking naturally-derived bioactive ingredients.

* Stringent Contaminant Control: Meets rigorous limits for heavy metals, residual solvents, and microbiological contaminants, crucial for global regulatory compliance.

* Comprehensive Documentation: We provide a full technical dossier including COA, MSDS, GMP Statement, Allergen Declaration (free from major allergens), and Non-GMO documentation.

* Scalability & Consistency: Produced in dedicated, large-scale batches, ensuring a stable, long-term supply of consistent quality for your production planning.

* Formulation Support: Our technical team can provide guidance on solubility enhancement strategies (e.g., with phospholipids or cyclodextrins) and formulation best practices.

Quercetin's broad-spectrum health benefits are supported by a substantial body of preclinical and clinical research, attributed to its multifaceted biological activities:

* Potent Antioxidant & Anti-inflammatory: Scavenges free radicals, chelates metal ions, and modulates key inflammatory pathways (e.g., NF-κB, COX-2), helping to manage oxidative stress and support a healthy inflammatory response.

* Immune System Modulation: Appears to support healthy immune function by stabilizing mast cells and modulating the release of histamine and other mediators, promoting balanced immune activity.

* Cardiometabolic Support: Research suggests it supports endothelial function, healthy blood pressure, and lipid metabolism, contributing to overall cardiovascular wellness.

* Cellular Health & Longevity: Acts as a senolytic agent (helping clear senescent "zombie" cells) and activates mitochondrial biogenesis via pathways like AMPK, supporting cellular energy and resilience.

* Synergistic Activity: Often combined with Vitamin C and Bromelain; Vitamin C helps recycle oxidized quercetin, enhancing its antioxidant capacity, while Bromelain may improve absorption and add complementary anti-inflammatory effects.

Research Reference: A 2020 randomized controlled trial published in "Frontiers in Immunology" highlighted the potential of Quercetin supplementation in supporting immune health and reducing the incidence of upper respiratory tract infections in athletic populations under physical stress.

Our Quercetin Dihydrate Powder is suitable for a variety of advanced nutraceutical delivery systems:

● Dietary Supplements:

* Capsules & Tablets: The primary application. Often used in doses from 250mg to 1000mg per serving. May require excipients for optimal flow and compaction.

* Powder Blends: Incorporated into immune-support or antioxidant complex blends in stick packs or canisters.

● Functional Foods & Beverages: Requires advanced delivery technology due to low water solubility. Can be used in fortified foods when paired with solubility-enhancing ingredients or specialized dispersion techniques.

● Targeted Formulations: Ideal for combination products focused on:

* Immune & Allergy Support: Paired with Zinc, Vitamin C, Echinacea.

* Joint & Muscle Health: Combined with Boswellia, Curcumin (with piperine), Glucosamine.

* Antioxidant & Longevity: Blended with Resveratrol, CoQ10, Pterostilbene.

JOYWIN founded in 2013 is an innovation-driven biotechnology company. we provide the manufacture of plant extracts, plant proteases, and customized products. We believe Good produce= Integrity+ Technology+Quality Control.

● R&D team of 40 members to provide full technical support.
● Years of successful experience with top food companies in the world.
● Dedicate on build long-term relationships with our clients and developing deeps partnership.

Q: What is the difference between Quercetin Dihydrate and Anhydrous Quercetin?
A: The key difference is the presence of two water molecules in the crystal lattice. The dihydrate form (C₁₅H₁₀O₇·2H₂O) typically has better stability, flowability, and is less electrostatic than anhydrous Quercetin (C₁₅H₁₀O₇). The potency is adjusted on a dried basis, so effective dosing is equivalent.

Q: Is your Quercetin Dihydrate suitable for vegan and allergen-free products?
A: Yes. Our product is 100% plant-derived, suitable for vegan formulations, and is processed in facilities free from major allergens. We provide supporting documentation.

Q: How do I address the poor water solubility of Quercetin in beverage applications?
A: For beverage applications, we recommend exploring solubility-enhanced forms like Quercetin Phytosome® (complexed with phospholipids) or using nanoparticle dispersion technologies. Our standard dihydrate powder is best suited for solid dosage forms.

Q: Can you provide stability data for this ingredient?
A: Yes. We have accelerated stability data (under ICH guidelines) available for our B2B clients to support your regulatory filings and product development.

Q: What certifications do you offer?
A: Our standard product is supported by Non-GMO documentation. We can also supply GMP, ISO 9001 facility statements, and support Kosher and Halal certification upon request.

Q: What is the typical lead time for an order?
A: For standard stock items, lead time is 10-15 working days after order confirmation. For larger custom orders, we will provide a specific timeline upon quotation.

Q：Where & how can I place an order?
A：You can click the inquiry on Quercetin dihydrate powder or send us an e-mail to contact@joywinworld.com.

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