Hair Wax Vacuum Homogenizer Mixer Mixing Making Machine

Hair Wax Vacuum Homogenizer Mixer Mixing Making Machine

Cas No: 9004-61-9
MF: C14H22NNaO11
Appearance:White powder
Function: Moisturizing
Grade :Cosmetics

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Product Introduction

Since the establishment, our company has been committed to the development and production of Red Yeast Rice Extract Powder, Dandelion Root Extract Powder, Goji Berry Juice Powder, always maintaining unconventional development ideas, and winning the appreciation and trust of customers with excellent quality and perfect service. Compared with our peers, we have not only the advantages in price, but also the incomparable advantages in quality and service. We will strive to achieve international business goals, and make us a brand with high technical starting point, excellent effect, complete variety, stable quality, and perfect after-sales service.

Products Description

JoyWin Natural presents pharmaceutical-grade Sodium Hyaluronic Acid Powder, the sodium salt of hyaluronic acid (HA). Engineered for superior performance, our product is the cornerstone ingredient for B2B manufacturers in the nutraceutical, cosmetic, and functional food industries seeking to harness the unparalleled hydrating and tissue-supporting properties of this vital molecule.

As a leading global supplier, we provide HA powder that is characterized by its exceptional purity, controlled molecular weight profiles, and batch-to-batch consistency. Whether your application targets joint health, skin hydration, ocular comfort, or advanced drug delivery, our Sodium Hyaluronate offers the versatility and reliability required for innovative and effective end-products.

 

Product Source & Fermentation Origin

JoyWin Natural's Sodium Hyaluronic Acid Powder is produced via a state-of-the-art bacterial fermentation process using non-pathogenic, non-GMO (upon request) strains of Streptococcus zooepidemicus. This method represents the gold standard for modern HA production, offering critical advantages over traditional animal-derived (rooster comb) extraction:

* Superior Purity & Safety: Eliminates risks associated with animal-borne pathogens (e.g., BSE) and allergens, ensuring a clean, vegan-friendly ingredient.

* Controlled Molecular Weight: Fermentation allows precise control over the polysaccharide chain length, enabling us to produce specific molecular weight ranges tailored to different absorption and functional needs.

* Scalability & Sustainability: A controlled, bioreactor-based process ensures a consistent, high-yield supply that is independent of animal sourcing constraints, aligning with ethical and sustainable sourcing principles.

* Traceability: Full batch documentation from raw material to finished product guarantees complete supply chain transparency.

 

Key Specifications & Composition

Our Sodium Hyaluronate is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. The key defining specification is its Molecular Weight (MW), which directly influences its functional properties:

Molecular Weight Type

Average MW Range

Key Characteristics

High Molecular Weight (HMW)

1,000 - 2,000 kDa+

Excellent surface moisturizing, film-forming; ideal for topical cosmetics and ocular lubricants.

Medium Molecular Weight

500 - 1,000 kDa

Balanced bioavailability; suitable for oral supplements targeting joint and skin health.

Low Molecular Weight (LMW)

50 - 500 kDa

Enhanced skin penetration and systemic absorption; optimal for advanced cosmeceuticals and nutraceuticals.

Oligo-HA / Nano-HA

< 50 kDa

High bioavailability, potential cellular signaling functions; for cutting-edge formulations.

We offer customized MW grades to meet specific application requirements.

Sodium Hyaluronic Acid Powder

 

Certificate of Analysis (COA) & Quality Parameters

 

Parameter

Specification

Test Method

Appearance

White or off-white, free-flowing powder or fibrous solid

Visual

Identification (IR)

Conforms to Reference Standard

USP / EP

Molecular Weight

As per ordered specification (e.g., 800 kDa ± 10%)

GPC / Intrinsic Viscosity

Purity (as Hyaluronic Acid)

≥ 95% (on dried basis)

Titration / Carbazole

Loss on Drying

≤ 10.0%

USP <731>

Protein Content

≤ 0.1%

Bradford / Lowry

Heavy Metals

   

- Lead (Pb)

≤ 5.0 mg/kg

ICP-MS

- Total Heavy Metals

≤ 20.0 mg/kg

USP <231>

Microbiological Tests

   

- Total Aerobic Microbial Count

≤ 100 CFU/g

USP <61>

- Total Yeast & Mold Count

≤ 10 CFU/g

USP <61>

- E. Coli

Negative

USP <62>

- Salmonella

Negative

USP <62>

- Staphylococcus aureus

Negative

USP <62>

Residual Solvents

Complies with ICH Q3C

GC

Endotoxin (for injectable grades)

< 0.05 EU/mg (available)

LAL Test

Available Certifications: cGMP, ISO 9001, DMF (Drug Master File) support, Kosher, Halal, Non-GMO Project Verified.

 

Production Process: cGMP & Precision Engineering

Our manufacturing adheres to strict cGMP guidelines, ensuring pharmaceutical-grade quality from start to finish.

1.Strain Inoculation & Fermentation: Selected bacterial strains are cultivated in a sterile, controlled bioreactor with a precise nutrient medium.

2.Biosynthesis & Harvest: During fermentation, bacteria synthesize and secrete hyaluronic acid into the fermentation broth. The process is monitored for optimal yield and MW control.

3.Cell Removal & Primary Purification: Bacterial cells are removed via microfiltration. The HA-containing broth undergoes a series of filtration and precipitation steps to remove proteins, nucleic acids, and other impurities.

4.Ultrafiltration & Purification: Multiple ultrafiltration/diafiltration steps are used to further purify the HA and begin adjusting the molecular weight distribution if needed.

5.Precipitation & Drying: The purified HA is precipitated with alcohol (e.g., ethanol), washed, and dried. The drying method (spray-dry, vacuum-dry, or freeze-dry) is selected based on the target MW and powder characteristics.

6.Milling & Blending: The dried material is milled to a uniform particle size and blended to ensure homogeneity within the batch.

7.QC Release & Packaging: The final powder undergoes full COA testing. Upon approval, it is packaged in double-layered, moisture-proof bags with desiccant in food-grade fiber drums.

 

Product Features & Competitive Advantages

* Pharmaceutical-Grade Purity: Exceptionally low protein and endotoxin levels, suitable for sensitive applications.

* Precise Molecular Weight Control: Tailored MW grades allow you to select the perfect HA for your formulation's mechanism of action (surface vs. systemic).

* High Water-Binding Capacity: Can retain up to 1000 times its weight in water, delivering exceptional hydrating efficacy.

* Excellent Solubility & Compatibility: Dissolves readily in water to form clear, viscous solutions compatible with most formulation bases.

* Stability & Safety: Highly stable under recommended storage conditions. Produced via fermentation for a vegan, allergen-free, and BSE/TSE-free profile.

* Full Regulatory Support: Comprehensive documentation suite (COA, TDS, MSDS, DMF, Letters of Guarantee) facilitates global regulatory submissions.

 

Documented Efficacy & Mechanism of Action

Sodium Hyaluronic Acid Powder is a fundamental component of connective tissue, synovial fluid, and skin, with efficacy supported by decades of clinical research.

* Joint & Bone Health: Oral supplementation with LMW HA is shown to be bioavailable. It reaches joints, where it supports synovial fluid viscosity, lubricates cartilage, and modulates inflammatory responses, thereby promoting comfort and mobility [Reference: Journal of Medicinal Food, etc.].

* Skin Health (Oral & Topical):

Oral: HA is absorbed and distributed to skin, where it enhances skin moisture, improves elasticity, and reduces wrinkle depth.

Topical: HMW HA forms a breathable, hydrating film on the skin surface, reducing transepidermal water loss (TEWL). LMW HA penetrates deeper to hydrate from within.

* Ocular Health: Used in eye drops for dry eye syndrome, providing long-lasting lubrication and protection for the corneal surface.

* Wound Healing: HA regulates inflammation and promotes tissue regeneration in the wound healing cascade.

* Antioxidant & Viscoelastic Properties: Acts as a free-radical scavenger and provides essential viscoelasticity to tissues.

 

B2B Application in Various Industries

Industry

Primary Applications

Recommended MW

Nutraceuticals & Dietary Supplements

Joint health capsules/tablets, skin beauty supplements, sports nutrition powders, liquid shots.

Low to Medium (50-1000 kDa)

Cosmetics & Skincare

Serums, moisturizers, masks, eye creams, lip products, anti-aging formulations.

Full range (LMW for penetration, HMW for film-forming)

Professional Skincare (Cosmeceuticals)

Mesotherapy, microneedling solutions, dermal fillers (requires specific high-grade).

Very Low to Medium

Ophthalmic

Artificial tears, lubricating eye drops, contact lens solutions.

High (≥1000 kDa)

Functional Food & Beverages

Beauty drinks, fortified waters, healthy aging products.

Low Molecular Weight (for solubility & absorption)

Pharmaceuticals

Drug delivery systems, viscosupplementation for osteoarthritis, wound dressings.

Varies by application; compliant with injectable grades available.

 

 packaging & shipping

* Standard Packaging: 1 kg, 5 kg aluminum foil bag inside a carton box. 20 kg in fiber drum with double PE bags and desiccant.

* Custom Packaging: Available (e.g., vacuum packing, nitrogen flush for maximum stability).

* Shelf Life: 36 months when stored in a cool (below 25°C), dry place in sealed, unopened containers. Avoid exposure to moisture and direct sunlight.

* Global Logistics: We are experts in international B2B shipping (EXW, FOB, CIF, DAP/DDP). All shipments include professional documentation (Commercial Invoice, Packing List, Certificate of Origin, Health Certificate if required).

* MOQ: Competitive Minimum Order Quantities are available. Contact us for details.

product-1040-500

 

Manufacturing Facilities

JOYWIN founded in 2013 is an innovation-driven biotechnology company. we provide the manufacture of plant extracts, plant proteases, and customized products. We believe Good produce= Integrity+ Technology+Quality Control.

product-1040-500

 

FAQ

Q1: What is the difference between Sodium Hyaluronate and Hyaluronic Acid?
A: Chemically, Sodium Hyaluronate is the sodium salt of hyaluronic acid. In practical terms for ingredient sourcing, they are often used interchangeably. The salt form (sodium hyaluronate) typically offers higher stability, better solubility in water, and a slightly lower viscosity at equivalent concentrations compared to the acid form, making it preferable for many formulations.

Q2: Which molecular weight is best for oral supplements targeting joint health?
A: Research indicates that Low Molecular Weight HA (e.g., 50-300 kDa) has superior oral bioavailability and is more effectively absorbed into the bloodstream and delivered to joint tissues compared to HMW HA.

Q3: Can I use your powder in sterile products or injectables?
A: We offer specific pyrogen-free, low-endotoxin grades suitable for such critical applications. Please contact our technical sales team to discuss your specific requirements, regulatory needs, and request the appropriate DMF or Master File documentation.

Q4: How does fermentation-derived HA compare to animal-derived HA?
A: Fermentation-derived HA is superior in terms of purity, consistency, and safety. It is free from animal proteins, has a lower risk of microbial contamination, and allows for precise control over molecular weight. It is also the preferred choice for vegan and allergen-conscious formulations.

Q5: What is the recommended usage percentage in cosmetic formulations?
A: Usage levels vary widely:

* Leave-on Skincare: 0.1% - 2.0%

* Rinse-off Products: 0.05% - 0.5%

* Serums & Treatments: Often 1% - 2%
Our Technical Data Sheet (TDS) provides recommended starting points. We recommend conducting compatibility and stability tests in your final formula.

Q6: How can I place an order on Sodium Hyaluronic Acid Powder?

A:You can click the inquiry or send us an e-mail to contact@joywinworld.com

 

At present, we have introduced advanced production equipment, strengthened quality inspections, and ensured that the exported Hair Wax Vacuum Homogenizer Mixer Mixing Making Machine are 100% qualified. Based on the advanced production equipment, exquisite technology and efficient management team, our company will continue to make efforts to innovate. We welcome customers to call us or write to inquire. If you wish to get more details about our company, Please contact with us now!

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