What is shiitake mushroom extract used for？

For over 6,000 years, shiitake mushrooms have held a place of extraordinary reverence in East Asian culture - prized not just as a culinary delicacy but as a potent medicinal food. Ancient Chinese texts described shiitake as the "elixir of life," and traditional Japanese medicine used it to boost energy, ward off illness, and promote longevity. Today, modern nutritional science is doing something remarkable: it is systematically validating what traditional healers knew intuitively.

Shiitake Mushroom Extract Powder has become one of the most commercially significant and scientifically studied functional mushroom ingredients in the global dietary supplement industry. Derived from Lentinula edodes - the world's second most widely cultivated edible mushroom - shiitake extract concentrates the bioactive compounds responsible for its remarkable health properties into a standardized, versatile powder that can be incorporated into capsules, functional foods, beverages, and nutraceutical formulations.

But what exactly is shiitake mushroom extract used for? The answer is broader and more clinically compelling than most people realize. From immune modulation and cancer support to cardiovascular protection, antiviral activity, gut health, and skin benefits, shiitake extract's applications span virtually every major category of preventive and therapeutic nutrition.

This comprehensive guide explores the full spectrum of shiitake mushroom extract's uses, grounded in the latest clinical and preclinical research. We'll examine the key bioactive compounds, review the evidence across each application area, discuss quality standards, and provide practical guidance for consumers and supplement formulators alike.

Part 1: What Is Shiitake Mushroom Extract Powder? Understanding the Basics

1.1 The Shiitake Mushroom - Lentinula edodes

Shiitake (Lentinula edodes) is a wood-decomposing fungus native to East Asia, where it grows naturally on decaying hardwood trees - particularly oak, chestnut, and beech. It is the second most cultivated edible mushroom globally (after button mushrooms), with annual production exceeding 10 million metric tons.

The mushroom's medicinal properties are concentrated in specific bioactive compounds that are present in both the fruiting body (the cap and stem) and the mycelium (the root-like network). Commercial Shiitake Mushroom Extract is produced from one or both of these sources, depending on the target bioactive profile.

1.2 How Shiitake Mushroom Extract Is Made

The production of high-quality Shiitake Mushroom Extract involves:

1.Cultivation: Shiitake is grown on hardwood logs (traditional method) or on supplemented sawdust substrate (modern commercial method). Log-grown shiitake is generally considered superior in bioactive content.

2.Harvesting: Fruiting bodies are harvested at peak maturity for maximum bioactive concentration

3.Drying: Low-temperature drying (freeze-drying or air-drying below 40°C) preserves heat-sensitive bioactives

4.Extraction: Hot water extraction (for polysaccharides/beta-glucans) or dual extraction (water + ethanol, for both polysaccharides and fat-soluble compounds)

5.Concentration and standardization: The extract is concentrated and standardized to specific bioactive markers

6.Spray-drying: The liquid extract is converted to a stable powder

The extraction method significantly affects the bioactive profile of the final product - a critical quality consideration for formulators and buyers.

1.3 Key Bioactive Compounds in Shiitake Mushroom Extract

The health benefits of Shiitake Mushroom Extract Powder are driven by a rich and complex array of bioactive compounds: ,

Lentinan A β-1,3/1,6-glucan polysaccharide - the most extensively studied and clinically validated bioactive compound in shiitake. Lentinan is a potent biological response modifier with well-documented immunomodulatory and antitumor properties. It has been approved as an adjunctive cancer treatment in Japan since 1985.

AHCC (Active Hexose Correlated Compound) A proprietary standardized extract derived from the mycelia of shiitake mushrooms, standardized to α-glucan content. AHCC is one of the most clinically studied natural immune modulators, with over 30 human clinical trials published.

Eritadenine (Lentinacin) A unique adenosine derivative found only in shiitake mushrooms. Eritadenine has demonstrated potent cholesterol-lowering effects by inhibiting S-adenosyl-L-homocysteine hydrolase - an enzyme involved in cholesterol metabolism.

Beta-glucans (β-1,3-D-glucan) Immunomodulatory polysaccharides that activate innate immune cells - particularly macrophages, natural killer (NK) cells, and dendritic cells - through pattern recognition receptors (Dectin-1, TLR-2).

Lenthionine A sulfur-containing compound responsible for shiitake's characteristic aroma; also demonstrates antimicrobial and antiplatelet properties.

Sterols (Ergosterol) A precursor to Vitamin D2; shiitake mushrooms exposed to UV light are one of the richest plant-based sources of Vitamin D.

Polyphenols and Flavonoids Antioxidant compounds that protect cells from oxidative damage and support anti-inflammatory pathways.

Dietary Fiber, B Vitamins, and Minerals Including riboflavin (B2), niacin (B3), pantothenic acid (B5), copper, selenium, and zinc - all essential for immune function and metabolic health.

Part 2: What Is Shiitake Mushroom Extract Used For? The Evidence-Based Applications

2.1 Immune System Modulation ⭐ Strongest Evidence

Immune support is the most extensively researched and clinically validated application of Shiitake Mushroom Extract Powder. The evidence spans basic science, animal studies, and multiple human clinical trials.

How shiitake modulates immunity:

Shiitake's beta-glucans - particularly lentinan - activate the immune system through a well-characterized mechanism: they bind to Dectin-1 receptors on macrophages, dendritic cells, and NK cells, triggering a cascade of innate immune activation that includes:

* Enhanced phagocytic activity of macrophages

* Increased natural killer (NK) cell cytotoxicity

* Activation of the complement system

* Stimulation of T-lymphocyte proliferation

* Enhanced production of interferon-gamma (IFN-γ) and interleukin-12 (IL-12)

A landmark review published in ScienceDirect (2025) on the therapeutic potential of shiitake mushrooms confirmed that shiitake exhibits potent immune-enhancing properties through lentinan and beta-glucan-mediated activation of innate and adaptive immune responses.

AHCC clinical evidence:

A comprehensive review published in PMC on the effects of AHCC - the standardized shiitake mycelium extract - documented that AHCC modulates the numbers and functions of immune cells including natural killer (NK) and T cells, which play critical roles in host defense against infection and cancer. The review analyzed multiple human clinical trials demonstrating AHCC's ability to:

* Increase NK cell activity by 200–300% in healthy adults

* Enhance dendritic cell function

* Improve T-cell counts and function in immunocompromised patients

* Reduce the duration and severity of upper respiratory infections

* Improve outcomes in cancer patients receiving chemotherapy

Practical immune support applications:

* Daily immune maintenance in healthy adults

* Enhanced immune support during cold and flu season

* Adjunctive immune support during cancer treatment

* Immune recovery after surgery or illness

* Support for individuals with chronic immune deficiency

2.2 Cancer Support and Oncology Applications ⭐ Strong Evidence

The use of shiitake mushroom extract in cancer support is one of the most clinically significant and well-documented applications - and one that sets shiitake apart from most other functional mushrooms.

Lentinan as an approved cancer adjunct:

Lentinan - the primary beta-glucan from shiitake - has been approved as an adjunctive cancer treatment in Japan since 1985, where it is administered intravenously alongside chemotherapy for gastric cancer. This regulatory approval is based on multiple clinical trials demonstrating that lentinan:

* Significantly extends survival in gastric cancer patients when combined with chemotherapy

* Improves quality of life during chemotherapy

* Reduces chemotherapy-related immunosuppression

* Enhances the tumor-killing activity of NK cells and cytotoxic T lymphocytes (CTL)

The ScienceDirect (2025) review confirmed that shiitake mushrooms exhibit potent anticancer properties by enhancing immune response and inhibiting tumor growth - mechanisms that include direct cytotoxicity against cancer cells, anti-angiogenic effects (inhibiting tumor blood vessel formation), and immune-mediated tumor surveillance.

Mechanisms of anticancer activity:

* Immunological: Lentinan activates NK cells, macrophages, and CTLs that directly kill cancer cells

* Anti-proliferative: Shiitake polysaccharides inhibit cancer cell division through cell cycle arrest

* Pro-apoptotic: Induces programmed cell death in cancer cells while sparing normal cells

* Anti-angiogenic: Inhibits VEGF-mediated tumor blood vessel formation

* Epigenetic: Modulates DNA methylation patterns in cancer cells

Important clinical note: Shiitake mushroom extract should be used as a complementary approach alongside conventional cancer treatment - not as a replacement for chemotherapy, radiation, or surgery. Always consult an oncologist before adding any supplement to a cancer treatment protocol.

2.3 Cardiovascular Health ⭐ Strong Evidence

Shiitake mushroom extract's cardiovascular benefits are among its most distinctive and well-characterized properties, driven primarily by the unique compound eritadenine.

Eritadenine and cholesterol reduction:

Eritadenine is found exclusively in shiitake mushrooms and has no equivalent in any other food or supplement. It lowers blood cholesterol through a unique mechanism: inhibition of S-adenosyl-L-homocysteine (SAH) hydrolase, an enzyme involved in the methylation cycle that affects cholesterol metabolism. This mechanism is distinct from statins and other cholesterol-lowering drugs, making eritadenine a potentially valuable complementary approach.

Animal studies have consistently shown that eritadenine supplementation reduces total cholesterol by 25–45% and LDL cholesterol by similar margins. Human studies using whole shiitake consumption have also demonstrated significant cholesterol-lowering effects.

Additional cardiovascular mechanisms:

* Beta-glucan fiber: Binds bile acids in the intestine, reducing cholesterol reabsorption (similar mechanism to oat beta-glucan)

* Lenthionine: Inhibits platelet aggregation, reducing thrombosis risk

* Antioxidant activity: Protects LDL cholesterol from oxidative modification - a key step in atherosclerosis development

* Anti-inflammatory effects: Reduces systemic inflammation, a major cardiovascular risk factor

* Homocysteine reduction: Eritadenine's effects on the methylation cycle may reduce homocysteine levels - an independent cardiovascular risk factor

2.4 Antiviral and Antimicrobial Activity ⭐ Moderate-Strong Evidence

Shiitake mushroom extract has demonstrated broad-spectrum antiviral and antimicrobial activity across multiple research models - a property that has attracted significant attention in the context of emerging infectious diseases.

Antiviral mechanisms:

* Immune activation: Enhanced NK cell and interferon production provides non-specific antiviral defense

* Direct antiviral activity: Lentinan and other polysaccharides have demonstrated direct inhibitory effects against multiple viruses including influenza, HIV, herpes simplex virus (HSV), and hepatitis B virus

* Inhibition of viral attachment: Sulfated polysaccharides from shiitake can interfere with viral binding to host cell receptors

WebMD notes that shiitake mushroom and AHCC extract have been studied for use in HIV/AIDS and other viral conditions, with some clinical evidence supporting immune benefits in HIV-positive individuals.

Antibacterial activity:

Lenthionine and other sulfur compounds in shiitake extract have demonstrated antibacterial activity against a range of pathogens, including Staphylococcus aureus, Streptococcus species, and Helicobacter pylori - the bacterium responsible for most gastric ulcers.

2.5 Gut Health and Microbiome Support ⭐ Emerging-Moderate Evidence

Shiitake mushroom extract's beta-glucan polysaccharides function as prebiotic fibers - selectively feeding beneficial gut bacteria and supporting a healthy, diverse gut microbiome.

Research has shown that shiitake polysaccharides:

* Selectively stimulate the growth of Bifidobacterium and Lactobacillus species

* Reduce populations of potentially pathogenic bacteria

* Enhance gut barrier integrity by promoting mucus layer production

* Stimulate secretory IgA production in the gut - the primary immune defense of the intestinal mucosa

* Reduce gut inflammation through SCFA production

A 2025 review in ScienceDirect noted that shiitake's bioactive compounds demonstrate significant gut microbiome modulation - an increasingly recognized mechanism through which medicinal mushrooms exert their systemic health effects.

The gut-immune axis connection is particularly relevant: approximately 70% of the immune system resides in gut-associated lymphoid tissue (GALT), and shiitake's combined prebiotic and immunomodulatory effects create a powerful synergistic benefit for overall immune health.

2.6 Anti-Inflammatory Effects ⭐ Strong Evidence

Chronic low-grade inflammation is the underlying driver of virtually all major chronic diseases - from cardiovascular disease and type 2 diabetes to neurodegenerative conditions and cancer. Shiitake mushroom extract demonstrates significant anti-inflammatory activity through multiple pathways:

* NF-κB inhibition: Shiitake polysaccharides suppress the master inflammatory transcription factor NF-κB, reducing expression of pro-inflammatory genes

* COX-2 inhibition: Reduces prostaglandin-mediated inflammation

* Cytokine modulation: Reduces pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) while preserving anti-inflammatory mediators

* Antioxidant activity: Reduces oxidative stress - a key driver of inflammatory signaling

The ScienceDirect (2025) therapeutic potential review confirmed shiitake's significant anti-inflammatory properties mediated through multiple signaling pathways, with applications across a broad spectrum of inflammatory conditions.

2.7 Liver Health and Hepatoprotection ⭐ Moderate Evidence

Shiitake mushroom extract has demonstrated hepatoprotective (liver-protecting) properties in multiple preclinical studies:

* Antioxidant protection: Reduces oxidative damage to hepatocytes (liver cells)

* Anti-fibrotic activity: May reduce liver fibrosis progression by inhibiting stellate cell activation

* Lipid metabolism: Eritadenine's effects on cholesterol metabolism reduce hepatic lipid accumulation

* Anti-inflammatory: Reduces liver inflammation markers (ALT, AST)

These properties make shiitake extract potentially valuable for individuals with non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease, or elevated liver enzymes.

2.8 Skin Health and Anti-Aging ⭐ Emerging Evidence

Shiitake mushroom extract is gaining significant traction in the cosmeceutical and beauty-from-within supplement categories, driven by several well-characterized mechanisms:

Kojic acid - a natural compound produced during shiitake fermentation - is one of the most widely used skin-brightening ingredients in cosmetics, inhibiting tyrosinase (the enzyme responsible for melanin production) to reduce hyperpigmentation and even skin tone.

Antioxidant protection: Shiitake's polyphenols and ergothioneine (a unique antioxidant amino acid found in high concentrations in mushrooms) protect skin cells from UV-induced oxidative damage and photoaging.

Collagen support: Shiitake's copper content and antioxidant activity support collagen synthesis and protection - key factors in maintaining skin elasticity and reducing wrinkle formation.

Anti-inflammatory effects: Reduce skin inflammation associated with acne, eczema, and rosacea. ,

2.9 Metabolic Health - Blood Sugar and Weight Management ⭐ Emerging Evidence

Emerging research suggests that shiitake mushroom extract may support metabolic health through several mechanisms:

* Blood sugar regulation: Beta-glucans slow carbohydrate absorption and improve insulin sensitivity

* Weight management: Eritadenine and beta-glucans may reduce fat accumulation and improve lipid metabolism

* Adiponectin modulation: Shiitake compounds may increase adiponectin - a hormone that improves insulin sensitivity and reduces inflammation

* Gut microbiome effects: Prebiotic activity supports microbiome profiles associated with metabolic health

2.10 Bone Health - Vitamin D Precursor ⭐ Moderate Evidence

Shiitake mushrooms are one of the few non-animal sources of Vitamin D. When exposed to UV light (sunlight or artificial UV), ergosterol in shiitake converts to ergocalciferol (Vitamin D2) - a biologically active form of Vitamin D that supports:

* Calcium absorption and bone mineralization

* Immune regulation

* Muscle function

* Cardiovascular health

UV-exposed shiitake mushroom powder can contain up to 46,000 IU of Vitamin D2 per 100g - making it a remarkable plant-based Vitamin D source. This is particularly relevant for Shiitake Mushroom Extract produced from UV-exposed mushrooms.

Part 3: Shiitake Mushroom Extract Powder vs. Whole Mushroom Powder - Key Differences

Understanding the distinction between whole mushroom powder and standardized extract powder is critical for both consumers and formulators:

For therapeutic applications - immune support, cancer adjunct, cardiovascular health - standardized Shiitake Mushroom Extract with verified beta-glucan content is the evidence-based choice. ,

Part 4: Quality Standards for Shiitake Mushroom Extract Powder

4.1 Key Quality Parameters

4.2 Extraction Method and Its Impact on Quality

Hot water extraction is the standard method for producing beta-glucan-rich shiitake extract. Hot water effectively extracts the water-soluble polysaccharides (beta-glucans, lentinan) that are responsible for most of shiitake's immune and health benefits.

Dual extraction (hot water + ethanol) additionally extracts fat-soluble compounds including eritadenine, sterols, and fat-soluble antioxidants - providing a more complete bioactive profile.

Important: The cell walls of mushrooms are composed of chitin - a tough polysaccharide that human digestive enzymes cannot break down. Extraction (rather than simple drying and grinding) is essential to release the bioactive compounds from within the cell walls and make them bioavailable. This is why standardized extract powder is significantly more potent than simple dried mushroom powder.

4.3 Standardization Markers

The most important quality marker for Shiitake Mushroom Extract Powder is beta-glucan content, typically expressed as a percentage:

* 10–20% beta-glucans: Entry-level therapeutic grade

* 20–30% beta-glucans: Standard therapeutic grade

* 30–50% beta-glucans: Premium therapeutic grade

Look for products with HPLC-verified beta-glucan content on the certificate of analysis (COA).

4.4 Certifications to Look For

Part 5: Dosage and Safety Guidelines

5.1 Evidence-Based Dosage

Based on the clinical literature, the following dosage ranges apply for Shiitake Mushroom Extract Powder:

For AHCC specifically, clinical trials have used doses of 3g/day for immune support in cancer patients, and 1–3g/day for general immune support in healthy adults.

5.2 Safety Profile

Shiitake mushroom extract has an excellent safety profile with centuries of culinary use and decades of clinical research. Reported side effects are generally mild:

* Shiitake dermatitis: A rare flagellate (whip-like) skin rash that can occur after consuming large amounts of raw or undercooked shiitake - caused by lentinan. Fully cooked or extracted shiitake does not cause this reaction.

* Gastrointestinal discomfort: Mild bloating or loose stools at high doses

* Eosinophilia: Rare; reported in some individuals taking high doses of shiitake extract

* Photosensitivity: Rare; reported in some clinical cases

5.3 Drug Interactions

5.4 Contraindications

* Autoimmune conditions (lupus, MS, rheumatoid arthritis): Immune stimulation may exacerbate autoimmune activity; consult physician

* Organ transplant recipients: Immune stimulation may increase rejection risk

* Pregnancy and breastfeeding: Insufficient safety data at supplemental doses; consult healthcare provider

* Mushroom allergy: Contraindicated

Part 6: Shiitake Mushroom Extract Powder in Supplement Formulations - For B2B Buyers

6.1 Best-Fit Product Categories

Shiitake Mushroom Extract is one of the most versatile and commercially proven functional mushroom ingredients:

* Immune health supplements - the primary application; pairs synergistically with reishi, turkey tail, maitake, and vitamin C

* Oncology support formulas - combines with AHCC, astragalus, and medicinal mushroom blends

* Cardiovascular health products - pairs with red yeast rice, CoQ10, and omega-3s

* Functional mushroom blends - the "5-mushroom" or "10-mushroom" blend category is one of the fastest-growing supplement segments

* Beauty-from-within supplements - pairs with collagen, vitamin C, and astaxanthin

* Gut health and microbiome products - combines with prebiotics and probiotics

* Sports nutrition and recovery - immune support for athletes; pairs with beta-glucans from oats and astragalus

6.2 Synergistic Mushroom Combinations

Shiitake extract pairs exceptionally well with other medicinal mushrooms in combination formulas:

6.3 Formulation Formats

Shiitake Mushroom Extract is compatible with:

* Capsules and tablets - most common; precise dosing; no taste issues

* Stick packs and sachets - convenient; mild earthy flavor is generally acceptable

* Functional beverages - mushroom coffee, tea blends, and elixirs

* Gummies - growing format; requires flavor masking for earthy notes

* Protein and superfood powders - adds functional mushroom value

* Functional foods - soups, broths, and culinary applications

Part 7: The Global Market for Shiitake Mushroom Extract Powder

The functional mushroom supplement market is one of the fastest-growing segments in the global nutraceutical industry, with shiitake extract at its commercial core:

* The global medicinal mushroom market was valued at approximately $8 billion in 2024 and is projected to exceed $15 billion by 2030

* Shiitake is consistently among the top 3 most popular medicinal mushrooms in supplement formulations globally

* The immune health supplement category - shiitake's primary market - has experienced sustained double-digit growth since 2020

* Consumer awareness of functional mushrooms has grown dramatically, driven by social media, wellness influencers, and mainstream media coverage

Key growth markets include:

* North America: Immune health, cancer support, and functional food applications

* Europe: Pharmaceutical-adjacent applications; strong clinical evidence requirements

* Japan and South Korea: Longest tradition of medicinal mushroom use; AHCC is mainstream

* China: Massive domestic market; shiitake is deeply embedded in food and medicine culture

* Southeast Asia and Australia: Rapidly growing functional food and supplement markets

Part 8: Frequently Asked Questions About Shiitake Mushroom Extract

Q: What is the difference between shiitake mushroom powder and shiitake mushroom extract powder? Shiitake mushroom powder is simply dried, ground mushroom with inconsistent and often low levels of active compounds (typically 5–15% beta-glucans). Shiitake Mushroom Extract is a concentrated, standardized product produced through hot water or dual extraction, with verified beta-glucan content (typically 20–50%). For therapeutic applications, standardized extract delivers significantly more consistent and potent effects.

Q: What is AHCC and how does it relate to shiitake extract? AHCC (Active Hexose Correlated Compound) is a proprietary standardized extract derived from the mycelia of shiitake mushrooms, standardized to α-glucan content. It is one of the most clinically studied natural immune modulators, with over 30 human clinical trials. Standard shiitake extract is derived from the fruiting body and standardized to beta-glucan content. Both are shiitake-derived but have different bioactive profiles and clinical evidence bases.

Q: Can shiitake mushroom extract help with cancer? Lentinan - the primary beta-glucan from shiitake - is approved as an adjunctive cancer treatment in Japan, where clinical trials have demonstrated survival benefits in gastric cancer patients when combined with chemotherapy. Shiitake extract should be used as a complementary approach alongside conventional cancer treatment, never as a replacement. Always consult an oncologist before adding any supplement to a cancer treatment protocol.

Q: How long does it take for shiitake mushroom extract to work? Immune activation effects (increased NK cell activity) can be measured within 1–2 weeks of consistent supplementation. Meaningful improvements in immune function, cardiovascular markers, and other health outcomes typically require 4–12 weeks of daily supplementation.

Q: Is shiitake mushroom extract safe for daily use? Yes - shiitake mushroom extract is safe for daily use at recommended doses for most healthy adults. The main precautions are for individuals with autoimmune conditions, organ transplant recipients, and those on immunosuppressive medications, who should consult their physician before supplementing.

Q: What is the best way to take shiitake mushroom extract ? Shiitake Mushroom Extract can be taken in capsules (most convenient for precise dosing), mixed into hot beverages (mushroom coffee or tea), blended into smoothies, or added to soups and broths. For immune support, taking it consistently at the same time each day produces the most reliable results.

Conclusion: Shiitake Mushroom Extract Powder - A Versatile, Science-Validated Functional Ingredient

The question "what is shiitake mushroom extract used for?" has a remarkably broad and well-supported answer. From its flagship application in immune modulation - backed by decades of clinical research and regulatory approval in Japan - to its distinctive cardiovascular benefits via eritadenine, its antiviral properties, gut health support, anti-inflammatory activity, hepatoprotection, skin health benefits, and metabolic support, Shiitake Mushroom Extract is one of the most comprehensively validated functional ingredients in the global supplement industry.

What makes shiitake extract particularly compelling is the convergence of traditional wisdom and modern science. The health properties that traditional East Asian medicine attributed to shiitake for thousands of years are now being systematically confirmed and mechanistically explained by rigorous scientific research. Lentinan's regulatory approval as a cancer adjunct in Japan is perhaps the most powerful validation of this convergence - a natural compound from a culinary mushroom earning a place in pharmaceutical oncology.

For consumers, shiitake mushroom extract represents a time-tested, science-backed investment in immune health, cardiovascular protection, and overall wellness. For supplement brands and formulators, it is a cornerstone functional mushroom ingredient with proven market demand, a robust and growing evidence base, and excellent formulation versatility. For healthcare professionals, it is a botanical worthy of serious consideration - particularly as an adjunctive support for patients managing immune challenges, cardiovascular risk, or cancer treatment.

At Joywin Natural, we supply premium-quality Shiitake Mushroom Extract Powder standardized to verified beta-glucan content, produced from carefully selected Lentinula edodes fruiting bodies using optimized hot water extraction processes. Our products are backed by comprehensive third-party testing for beta-glucan content, heavy metals, pesticide residues, and microbiological safety. With certifications including cGMP, ISO 22000, FSSC 22000, Organic (NOP/JAS), Kosher, Halal, and more, we are the trusted ingredient partner for supplement brands that demand quality without compromise. If you want to know more about it or are interested in purchasing it, you can send an email to contact@joywinworld.com. We will reply to you as soon as possible after we see the message.