Reduced Glutathione Powder

Welcome to the pinnacle of antioxidant ingredient technology. Our Pharmaceutical Grade Reduced glutathione powder delivers the biologically active form of the body's most crucial endogenous antioxidant in its purest, most bioavailable form. As the "master antioxidant," Glutathione is tripeptide composed of L-Glutamine, L-Cysteine, and L-Glycine, essential for cellular defense, detoxification, and immune function.

We supply high-purity, fermented Glutathione to B2B partners in the dietary supplement, nutraceutical, and functional food industries. Empower your formulations with an ingredient backed by extensive clinical research for supporting liver health, skin vitality, athletic recovery, and overall cellular resilience.

Purity Through Precision Fermentation. Unlike older extraction methods or chemical synthesis, our Reduced Glutathione is produced via a state-of-the-art, patented yeast fermentation process (Saccharomyces cerevisiae). This bio-fermentation technology ensures:

* High Bioavailability: Produces the natural, bioactive L-form and Reduced form of Glutathione that the human body can effectively utilize.

* Non-GMO & Allergen-Free: The fermentation substrate is rigorously controlled, resulting in a final product that is non-GMO, gluten-free, and free from major allergens. The yeast is completely removed during purification.

* Superior to Synthetic: Fermentation mimics natural biological pathways, avoiding the racemic mixtures (D- and L- forms) and residual solvents that can be associated with chemical synthesis.

* GRAS Status: Our production process and ingredient are compliant for use in dietary supplements and specific food categories.

Our product is defined by its specific molecular structure and high purity, ensuring consistent biological activity.

We guarantee uncompromising quality and purity. Each batch is accompanied by a comprehensive COA.

Standard Specifications (COA):

Our proprietary fermentation and purification process ensures the highest yield of bioactive Reduced Glutathione.

* Strain Selection & Inoculation: Selected non-GMO yeast strains (Saccharomyces cerevisiae) with high Glutathione production efficiency are cultivated in a sterile fermenter.

* Precision Fermentation: The yeast undergoes controlled fermentation in a optimized nutrient medium. During this phase, the yeast cells naturally synthesize and accumulate Reduced Glutathione.

* Cell Lysis & Extraction: The yeast cells are gently lysed using enzymatic or physical methods to release the intracellular Glutathione without degrading it.

* Multi-Stage Purification: The crude extract undergoes a series of advanced purification steps, including ultra-filtration, ion-exchange chromatography, and activated carbon treatment, to remove proteins, nucleic acids, yeast debris, and impurities.

* Crystallization & Drying: The purified Glutathione solution is concentrated under vacuum and crystallized under controlled conditions. The crystals are then collected and dried at low temperatures to preserve the reduced form.

* Stability Packaging: The final powder is packaged in double-layer, vacuum-sealed bags with desiccants, under a nitrogen atmosphere to prevent oxidation.

* Pharmaceutical Grade Purity: ≥98.0% assay ensures high potency and efficacy in your formulations.

* Fermented & Bioactive: Produced via yeast fermentation, delivering the natural, reduced L-form that is readily recognized by the body.

* Minimal Oxidized Form (GSSG): Rigorously controlled to ≤2.0%, ensuring maximum antioxidant capacity upon ingestion.

* Superior Stability: Our specialized packaging and processing minimize oxidation during storage and handling.

* Fully Traceable & Compliant: Supported by full documentation, including DMF (Drug Master File) where applicable, facilitating your regulatory submissions.

* Solubility: Freely soluble in water, making it suitable for a wide range of delivery systems.

The role of Reduced glutathione powder is well-established in biochemical literature and clinical studies.

* The Master Antioxidant: GSH directly neutralizes free radicals and reactive oxygen species (ROS) and is essential for recycling other antioxidants like Vitamin C and E. [Reference: Free Radical Biology and Medicine]

* Liver Detoxification & Protection: It is a critical cofactor for Phase II detoxification enzymes in the liver, conjugating with and neutralizing toxins, heavy metals, and pharmaceuticals. Clinical studies support its use in supporting liver function. [Reference: Journal of Clinical Gastroenterology]

* Immune System Modulation: GSH is vital for the optimal function of lymphocytes, enhancing the body's defense against pathogens and supporting a balanced immune response.

* Cellular Energy Production: Essential for mitochondrial function, GSH helps protect the mitochondria from oxidative damage, supporting cellular energy (ATP) production.

* Skin Health & Brightening: It inhibits the enzyme tyrosinase, which is involved in melanin production, leading to its widespread use in skin whitening and anti-aging formulations. [Reference: International Journal of Cosmetic Science]

* Athletic Performance & Recovery: Strenuous exercise increases oxidative stress. Supplementation can help reduce muscle fatigue, decrease recovery time, and improve performance.

Formulate with this versatile, powerful ingredient across multiple high-value categories.

* Dietary Supplements: Capsules, tablets (requires protective coating or matrix to prevent oxidation), and two-piece hard shell capsules.

* Effervescent Tablets & Powdered Drinks: Ideal for its high solubility, creating convenient and fast-acting antioxidant and liver support products.

* Skin Health & Beauty Supplements: A key active in oral beauty formulations aimed at skin brightening, anti-aging, and detoxification.

* Sports Nutrition: Incorporated into pre- and post-workout formulas to combat exercise-induced oxidative stress.

* Functional Food & Beverages (Emerging): For advanced functional shots and health beverages, though stability in liquid formats requires careful formulation.

* Recommended Clinical Dosage: Typical effective doses in clinical studies range from 250 mg to 1000 mg per day.

We protect the integrity of this sensitive molecule from our facility to yours.

* Standard Packaging:

1 kg in a double-layer polyethylene bag, vacuum-sealed and placed in an aluminum foil bag with an oxygen absorber, inside a cardboard box.

5 kg / 10 kg in a double-layer polyethylene bag inside a plastic drum with desiccant.

* Custom Packaging: Nitrogen flushing and other custom barrier solutions are available to meet specific stability requirements.

* Storage: Store in a cool, dry place at 2-8°C (36-46°F) for long-term stability. Keep containers tightly sealed under an inert atmosphere. Shelf life: 24 months when stored properly.

* Global Logistics: We specialize in cold-chain international shipping for temperature-sensitive ingredients, ensuring the product maintains its reduced state and purity during transit.

JOYWIN founded in 2013 is an innovation-driven biotechnology company. we provide the manufacture of plant extracts, plant proteases, and customized products. We believe Good produce= Integrity+ Technology+Quality Control.

JOYWIN attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

Q1: What is the difference between Reduced (GSH) and Oxidized (GSSG) Glutathione?
A1: Reduced Glutathione (GSH) is the active, antioxidant form that quenches free radicals. When it does so, it becomes oxidized (GSSG), where two molecules are linked by a disulfide bond. The body must recycle GSSG back to GSH. Our product is predominantly in the active Reduced form, ensuring immediate biological activity.

Q2: Is oral Glutathione effectively absorbed?
A2: Yes. While it was once believed to be poorly absorbed, modern clinical studies using high-purity, reduced Glutathione (like ours) have demonstrated its bioavailability. Research shows it raises blood and tissue levels of GSH, supporting its efficacy when delivered in protective, high-quality formulations. [Reference: European Journal of Nutrition]

Q3: How do you ensure the product remains in its reduced form during storage and transit?
A3: We employ a multi-faceted approach: 1) Production under controlled, low-oxygen conditions. 2) Rigorous control of moisture content. 3) Final packaging with vacuum, nitrogen flushing, and oxygen scavengers. 4) Recommended cold-chain storage.

Q4: What is your minimum order quantity (MOQ)?
A4: Our standard MOQ is 1 kg. Sample quantities (100g) are available for qualified B2B partners for R&D, stability testing, and pilot production.

Q5: Can this be used in liposomal formulations?
A5: Absolutely. Our high-purity, fine powder is an excellent starting material for liposomal Glutathione production, as the purity minimizes interference with the liposome formation process.

Q6: Do you provide regulatory support for international markets?
A6: Yes. We provide comprehensive technical dossiers, COAs, and can supply documentation to support your NDI (New Dietary Ingredient) submissions to the FDA or other regulatory filings for markets like the EU, Canada, and Australia.

Q7：How can we contact you?
A7：You can click the inquiry on Reduced glutathione powder or send us an e-mail to contact@joywinworld.com.

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